You are here
Your Questions ... Answered ... Facts
What is Scleroderma?
Scleroderma is a chronic, degenerative, autoimmune disorder that leads to the over-production of collagen. It is characterized by a hardening or sclerosis in the skin or other organs. The systemic type — systemic sclerosis — can be fatal, as a result of heart, kidney, lung or intestinal damage.
Until now, there was no treatment that controlled or stopped the underlying problem: the over-production of collagen in all forms of scleroderma. Thus, treatment and management focus on relieving symptoms and limiting damage.
Is there a cure for scleroderma?
Stem cell transplants appear to be the most likely candidate as a cure. Mortality rates for first transplant patients were 15 percent. The current mortality rate is 2.5 to 3 percent. Approximately 40 percent of recent patients have experienced sustained remission. If these patients can remain symptom-free for a 20-year period, then yes, you could describe stem cell transplants as a cure.
There are websites offering a cure for scleroderma. Are they legitimate?
If someone is offering a cure, ask if they have the deed to the London Bridge, because you would like to buy both in a package deal. A small percentage of scleroderma sufferers will get better no matter what they take. They are the fortunate minority and not the cured!
Halofuginone has been in the news as a scleroderma treatment. Is it available?
Yes, Halofuginone is available at your local vet supply. Halofuginone is a coccidiostat used in veterinary medicine. Any sane person considering self-dosing with Halofuginone should first write their Last Will and Testament because they will be dead in a very short order! Case in point: At 6 parts per million, chickens will do quite well, but at 12 parts per million they die!
When was Halofuginone first identified as a scleroderma treatment?
On March 10, 2000, Collgard Biopharmaceuticals announced that it received orphan drug designation from the U.S. Food and Drug Administration (FDA) for Halofuginone as a scleroderma treatment.
What is Halofuginone?
In the 1960s, U.S. Army scientists created a Febrifugine derivative called Halofuginone as a possible malaria drug. From an abstract: Febrifugine and its derivatives, including Halofuginone, which possesses very high activity against malaria. Halofuginone was observed to be the best among the synthesized derivatives of Febrifugine.
Should I use Halofuginone?
Absolutely not. Once again, any sane person considering self-dosing with Halofuginone should first write their Last Will and Testament!
Why was the recent mention of Halofuginone in the news so important?
Researchers have discovered that a small-molecule compound known as Halofuginone inhibits the development of Th17 cells, immune cells recently recognized as important players in autoimmune diseases. The researchers show that Halofuginone prevents the development of Th17 cells in both mice and humans, halts the disease process they trigger, and is selective in its effects. It also has the potential to be taken orally.
When can I expect to be able to get a prescription for Halofuginone?
Halofuginone has been identified as a key player. Still to be discovered is the transporting agent the vehicle by which “low dose” Halofuginone can be delivered to specific targets. Once that has been discovered, you should be able to get Halofuginone in three to five years. So the best guess estimate: You should be able to get Halofuginone in 8 to 10 Years from today! Maybe!
Numerous articles mention Chang Shan and Halofuginone together. Why?
Halofuginone is a synthetic analog made from Febrifugine, and Chang Shan (Dichroa Root - Latin botanical name) is the organic source for Febrifugine.
Does Sclero-Eze contain Chang Shan?
Yes, Sclero-Eze contains Chang Shan appropriately and proportionally blended with nine other herbs and a mineral.
Are all Chang Shan products equal?
No. The effectiveness varies greatly among various suppliers. All the single-herb Chang Shan products available over-the-counter to consumers were tested and all failed. Sclero-Eze's Chang Shan is available only through acupuncturists and Chinese herbal practitioners.
Why do doctors seem uninterested in herbal supplements?
There are two distinct reasons. First, they are educated to use criteria applicable to the pharmaceutical industry. Thus, their educational base instills a bias that places scientific measures before the truth. Simplistically, if you can’t prove it then it doesn’t exist! Second, herbal supplements are considered a food, and there have been gross negligent claims regarding the merits of the foods we are consuming!
Are Herbal supplements safe?
Herbal supplements are as safe as peanut butter unless you're allergic to peanut butter. Contact your health care practitioner before using any herbal supplement.
Is Sclero-Eze safe?
Sclero-Eze has been refined to have the broadest application use among scleroderma sufferers. In essence, it has been made as safe as possible for its specific use!
How long before I notice any difference?
Many individuals will take as long as ten to sixteen weeks to notice any change, depending on the severity of their illness. A few may notice the change in as little as six weeks. Be patient and report anything out of the ordinary to your health care practitioner.
What happens if I stop taking Sclero-Eze?
You will regress and get sick again. The timeline can be as little as 5 days to three weeks! While you are deciding whether or not Sclero-Eze is working for you, please try to be consistent, as it will be reflected in your final decision!
Thank you for considering Sclero-Eze. Because I have this disease, I can be genuinely empathetic toward your situation, and I would never offer you false hope!
Ervin D. Gonzales